Melanoma may be one of the least common skin cancers, but it is
still the most deadly. New hope might be on the horizon for people with
this disease, however, in the form of an existing drug used to treat
arthritis.
Researchers suggest that an arthritis drug could help to combat melanoma.
Researchers from the University of East Anglia (UEA) in the United
Kingdom reveal how adding leflunomide — an immunosuppressive drug used
for treating rheumatoid arthritis — to a current melanoma treatment halted the growth of melanoma cancer cells in mice.
The teams promising findings were recently published in the journal Oncotarget.
Melanoma is a form of skin cancer
that begins in melanocytes, which are skin cells that produce melanin —
that is, the pigment that helps to protect our skin from the sun, and
which gives the skin its "tan" color.
According to the American Cancer Society (ACS), melanoma accounts for just 1 percent of all skin cancers, but it is responsible for a large proportion of skin cancer deaths.
This year alone, around 9,730 people in the United States are
expected to die from melanoma, highlighting the need for more effective
treatments.
Lead researcher of the new study Dr. Grant Wheeler, of the School of
Biological Sciences at UEA, and colleagues believe that leflunomide
could help to meet this need by boosting existing melanoma treatments.

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